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H9c2 cells treated with WY-14643 were more resistant against hypoxia-reoxygenation injury. Cells were incubated with medium containing 0 to 100 μM of WY-14643 for 24 h before 20 h of hypoxia and 2 h of reoxygenation. MTT assay shows that cell viability was increased with treatment of WY-14643 10 μM or greater. ∗ P < 0.05 versus WY-14643 0 μM (n = 3). ∗ P < 0.05 versus WY-14643 0 μM (n = 3). HR: hypoxia-reoxygenation.
