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. 2015 Dec 7;2016:4597246. doi: 10.1155/2016/4597246

Figure 1.

Figure 1

Spectrum of NAFLD. Obesity, genetic factors, and insulin resistance (IR) contribute to fat deposition in the liver. Approximately 30% of patients with NAFLD have NASH, which involves the presence of various degrees of inflammation and fibrosis, and can progress to cirrhosis in 20–25% of cases within 20 years. An unknown percentage of cases develop HCC. Adapted from Trauner et al., 2010 [9].