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Histologic section of pancreas: (a) control rats—normal pancreatic structures were observed, (b) the rats subjected to cerulein-induced pancreatitis (AP) alone—evidences of edema, vacuolization, inflammatory cell infiltrate, and necrosis were noted, (c, d) the AP animals treated with tempol—note the significant reduction in edema, vacuolization, and inflammation, without any evidence of necrosis as compared to untreated animals (b). H&E staining; original magnification, ×20.
