Table 3. 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromid (MTT) assay detected the role of microRNA-122 (miR-122) in inhibiting QBC939 cell proliferation.
Group | 0 h | 24 h | 48 h | 72 h |
---|---|---|---|---|
Blank group | 0.494 ± 0.053 | 0.711 ± 0.047 | 1.029 ± 0.054 | 1.360 ± 0.059 |
Mock group | 0.508 ± 0.055 | 0.705 ± 0.051 | 1.015 ± 0.075 | 1.355 ± 0.063 |
NC group | 0.514 ± 0.051 | 0.690 ± 0.037 | 0.995 ± 0.067 | 1.340 ± 0.045 |
miR-122 mimic group | 0.502 ± 0.055 | 0.637 ± 0.041 | 0.776 ± 0.059a,b,c | 0.829 ± 0.050a,b,c |
anti-miR-122 group | 0.514 ± 0.066 | 0.752 ± 0.059 | 1.175 ± 0.026a,b,c,d | 1.855 ± 0.039a,b,c,d |
F | 0.069 | 2.286 | 17.860 | 146.300 |
P | 0.990 | 0.132 | <0.001 | <0.001 |
Note: NC: negative control.
acompared to the blank group, P < 0.05.
bcompared to the mock group, P < 0.05.
ccompared to the NC group, P < 0.05.
dcompared to the miR-122 group, P < 0.05.