Figure 1. Sequence alignment of SSRP1-M with its homologues.

The amino acid sequences of the 10 indicated species from human to yeast are aligned, with the secondary structural elements reported in this paper indicated above the sequences. The amino acids involved in the hydrophobic inter-domain interactions are designated with yellow triangles; residues involved in stabilizing the extra βαβ super-secondary structure are designated with green triangles; residues comprising the positively charged regions for dsDNA binding are designated with black triangles; and residues comprising the unique negatively charged regions are designated with magentas stars.