Table II.
Grade 2 or 3 toxicity attributable to rigosertib by dose level
| Initial dose level (mg) | Patients treated | Patients with grade 2 or 3 drug-related toxicity (%) |
|---|---|---|
| 70 | 3 | 1 (33) |
| 140 | 2 | 0 |
| 280 | 2 | 0 |
| 560 | 24 | 11 (46) |
| 700 | 6 | 5 (83) |
| All | 37 | 17 (46) |
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