Table 1.
Effect of I. Latifolia on Spontaneous Motor Activity and Motor Coordination in Mice
| Group | Dose | Activity (% of prevalue)a | Number of mice which fell downb |
|---|---|---|---|
| Sham | — | 77.0 ± 9.3 | 0 |
| Aβ (25–35) | 15 nmol | 61.1 ± 7.2 | 0 |
| +I. latifolia | 25 mg/kg | 78.6 ± 10.0 | 0 |
| +I. latifolia | 50 mg/kg | 67.0 ± 10.6 | 0 |
| +I. latifolia | 100 mg/kg | 72.8 ± 12.6 | 0 |
a
After the retention trial for the passive avoidance test, a spontaneous activity was measured using a locomotor activity monitor.
b
Motor coordination was measured with a rota rod treadmill. Mice that fell off the rod within 2 min were counted. Values are expressed as the mean ± SEM (n = 12–14 mice/group).
SEM, standard error of the mean.