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. 2016 Jan 5;371(1685):20150055. doi: 10.1098/rstb.2015.0055

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© 2015 The Author(s)

Published by the Royal Society. All rights reserved.

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Figure 5. — Anti-DC0 and anti-pCaMKII resolve a substantial brain in the acoel S. roscoffensis. (a–d) Both antisera (DC0 in a,b; anti-pCaMKII in d,e) resolve a bilaterally symmetric region anterior to the statocyst. The origins of caudally directed nerve cords resolved by antisera against synaptotagmin (c), elav (f) and serotonin domains (see figure 6) (adapted from [66,77]) demonstrate their overlap within restricted regions of the DC0- (c) and anti-pCaMKII (f)-positive domains. Together, these relationships suggest a brain within which there are circumscribed tracts, neuropils and modulatory pathways.