Table 2.
SNPs involved in significant interactions. Columns from left to right are: SNP identifier, region in which the SNP is located, gene, Frequencies in the cases, frequencies in the controls, ORs and 95 % of confidence interval (CI), nominal p-value and adjusted p-value
| Analysis | SNP | Region | Gene | Frequency cases | Frequency controls | OR [95 % CI] | P-value | Adjusted p-value |
|---|---|---|---|---|---|---|---|---|
| sMTC | rs4758915 | Intronic | CHFR | 0.03704 | 0.02586 | 1.449 [0.4003–5.243] | 0.5702 | 0.9812 |
| sMTC | rs10402530 | Downstream | AC016582.2 | 0.1944 | 0.1897 | 1.031 [0.5782–1.84] | 0.9167 | 0.9936 |
| sMTC | rs7835921 | Intronic | C8orf37 | 0.4519 | 0.5086 | 0.7966 [0.5008–1.267] | 0.3365 | 0.9669 |
| sMTC | rs1287079 | Downstream | RNU1-55P | 0.3019 | 0.3664 | 0.7479 [0.4567–1.225] | 0.2476 | 0.9569 |
| jPTC | rs2235544 | Intronic | DIO1 | 0.4667 | 0.5043 | 0.86 [0.487–1.519] | 0.6032 | 0.9696 |
| jPTC | rs16876356 | Intronic | DMGDH | 0.1167 | 0.2308 | 0.4403 [0.1891–1.025] | 0.0518 | 0.9007 |
| jPTC | rs17716031 | Intronic | RP11-648K4.2 | 0.1034 | 0.1336 | 0.7481 [0.2964–1.888] | 0.5379 | 0.9668 |
| jPTC | rs10775207 | Intronic | LOXL1 | 0.0167 | 0.0087 | 1.932 [0.1723–21.67] | 0.5868 | 0.9668 |