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. 2015 Dec 21;5:18588. doi: 10.1038/srep18588

Figure 3. Deletion of Paneth cells impairs the expression of FABP4, adipsin and adiponectin in gut crypt cells.

Figure 3

(a,b) qRT-PCR (a) and immunoblot analyses (b) of intestinal crypts with and without dithizone treatments. The mice were intravenously injected by dithizone and killed at the indicated time (male, n = 6 or indicated number). R. E., relative expression. (c) Serum levels of FABP4, adipsin and adiponectin in mice with (6h, 12h and 6 days after dithizone) and without (0h) dithizone treatments. (d) Serum levels of glucose (Glu), triglyceride (TG) and cholesterol (CHO) in fasting mice with (6h, 12h and 6 days after dithizone) and without (0h) dithizone treatments. *P < 0.05 and **P < 0.01 (t-test, mean ± SD in a; Mann-Whitney U test in c,d). The data were a representative of three independent experiments.