Table 1. Estimated parameters for the non-strain-specific model fit to the Carenet-NCSF data.
Parameter | Symbol | Initial range | Prior dist-ribution | Model 1 | Model 2 | Model 3 | Model 4 | Model 5 | Model 6 | Model 7 | Model 8 | Model 9 | Model 10 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Basic reproductive number | R0 = β0/γ | 15 to 30 | U (5,30) | 20.0 | 17.3 | 15.5 | 19.5 | 15.1 | 20.9 | 13.6 | 21.6 | 17.3 | 15.8 |
Relative infectiousness of mild/asymptomatic infections | ρA | 0.1 to 0.3 | U (0,0.5) | 0.16 | 0.19 | 0.23 | 0.16 | 0.24 | 0.11 | 0.29 | 0.12 | 0.19 | 0.23 |
Amplitude of seasonality in transmission | b | 0.05 to 0.1 | U (0,0.3) | 0.095 | 0.086 | 0.084 | 0.094 | 0.085 | 0.089 | 0.081 | 0.095 | 0.086 | 0.084 |
Seasonal offset | ϕ | −0.03 to 0.07 years | U (−0.5,0.5) | −0.022 | 0.020 | 0.011 | 0.008 | −0.028 | 0.015 | 0.008 | −0.004 | 0.009 | 0.005 |
Duration of temporary immunity | 1/ω | 26 to 39 weeks | U (26,52) | 28.4 | 32.4 | 31.3 | 31.4 | 26.5 | 30.5 | 30.9 | 31.9 | 35.0 | 35.9 |
Proportion of vaccinees receiving protection equal to two natural infections | ξ | 0.2 to 0.8 | U (0,1) | 0.48 | 0.59 | 0.37 | 0.90 | 0.71 | 0.29 | 0.85 | 0.43 | 0.89 | 0.98 |
Hospitalization/reporting rate among < 2 year olds | h0 | 0.48 to 0.52 | U (0,1) | 0.52 | 0.51 | 0.43 | 0.50 | 0.48 | 0.50 | 0.44 | 0.52 | 0.55 | 0.53 |
Relative rate of hospitalization among ≥ 3 year olds | η | 0.2 to 0.6 | U (0,1) | 0.28 | 0.20 | 0.21 | 0.23 | 0.23 | 0.20 | 0.25 | 0.31 | 0.15 | 0.15 |
Log posterior | −5,191 | −5,290 | −5,218 | −5,112 | −5,243 | −5,366 | −5,236 | −5,191 | −5,137 | −5,098 | |||
Model validation | |||||||||||||
Hospitalization/reporting rate among < 2 year olds at GUH | hG | NA | U (0,1) | 0.0155 | 0.0168 | 0.0164 | 0.0163 | 0.0164 | 0.0171 | 0.0163 | 0.0155 | 0.0176 | 0.0175 |
Log posterior | −7,288 | −7,267 | −7,271 | −7,273 | −7,271 | −7,265 | −7,273 | −7,287 | −7,264 | −7,264 |