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. 2015 Dec 21;5:18585. doi: 10.1038/srep18585

Table 1. Estimated parameters for the non-strain-specific model fit to the Carenet-NCSF data.

Parameter Symbol Initial range Prior dist-ribution Model 1 Model 2 Model 3 Model 4 Model 5 Model 6 Model 7 Model 8 Model 9 Model 10
Basic reproductive number R0 = β0/γ 15 to 30 U (5,30) 20.0 17.3 15.5 19.5 15.1 20.9 13.6 21.6 17.3 15.8
Relative infectiousness of mild/asymptomatic infections ρA 0.1 to 0.3 U (0,0.5) 0.16 0.19 0.23 0.16 0.24 0.11 0.29 0.12 0.19 0.23
Amplitude of seasonality in transmission b 0.05 to 0.1 U (0,0.3) 0.095 0.086 0.084 0.094 0.085 0.089 0.081 0.095 0.086 0.084
Seasonal offset ϕ −0.03 to 0.07 years U (−0.5,0.5) −0.022 0.020 0.011 0.008 −0.028 0.015 0.008 −0.004 0.009 0.005
Duration of temporary immunity 1/ω 26 to 39 weeks U (26,52) 28.4 32.4 31.3 31.4 26.5 30.5 30.9 31.9 35.0 35.9
Proportion of vaccinees receiving protection equal to two natural infections ξ 0.2 to 0.8 U (0,1) 0.48 0.59 0.37 0.90 0.71 0.29 0.85 0.43 0.89 0.98
Hospitalization/reporting rate among < 2 year olds h0 0.48 to 0.52 U (0,1) 0.52 0.51 0.43 0.50 0.48 0.50 0.44 0.52 0.55 0.53
Relative rate of hospitalization among ≥ 3 year olds η 0.2 to 0.6 U (0,1) 0.28 0.20 0.21 0.23 0.23 0.20 0.25 0.31 0.15 0.15
Log posterior       −5,191 −5,290 −5,218 −5,112 −5,243 −5,366 −5,236 −5,191 −5,137 −5,098
Model validation
 Hospitalization/reporting rate among < 2 year olds at GUH hG NA U (0,1) 0.0155 0.0168 0.0164 0.0163 0.0164 0.0171 0.0163 0.0155 0.0176 0.0175
 Log posterior       −7,288 −7,267 −7,271 −7,273 −7,271 −7,265 −7,273 −7,287 −7,264 −7,264