Figure 2. α-MSH at different doses corrected the overexpression of proinflammatory factors in the ocular surface of the dry eye rats at the end of the experiment.
The animals were divided into NaCl + NaCl, D + NaCl, D + 10−5 α-MSH, D + 10−4 α-MSH, and D + 10−3 α-MSH groups. On day 28, the relative expression levels of the proinflammatory factors, including TNF-α (A), IL-1β (B), and IFN-γ (C) in the corneas and conjunctivas were measured by qPCR. n = 6 per group. *p < 0.05, **p < 0.01, ***p < 0.001. D = dry eye, NaCl = saline.