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The animals were divided into NaCl + NaCl, D + NaCl, D + 10−4 α-MSH, D + H89 + 10−4 α-MSH, D + PD + 10−4 α-MSH, and D + DMSO + 10−4 α-MSH groups. The effects of α-MSH and the pharmacological blockers, H89 and PD98059, on corneal morphology in the dry eye rats were examined by H&E staining on Day 28. n = 8 per group. D = dry eye, NaCl = saline, PD = PD98059.
