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. 2015 Aug 20;11(11):2705–2715. doi: 10.1080/21645515.2015.1019186

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Published with license by Taylor and Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 4. — AdCA trial: ex vivo ELISpot IFN-γ activities to CSP and AMA1. The associations of fold-changes of pre-CHMI and post-CHMI activities with pre-CHMI activities are shown as log-transformed values, and the dotted line represents no-change. The shaded box shows ±1.5 range. (A) CSP: there was a significant negative association between fold-change and pre-CHMI activities; activities of all 13/17 positive before CHMI fell after CHMI. (B) AMA1: although activities of all 17/17 subjects that were positive pre-CHMI all fell after CHMI, there was no relationship between fold-change and pre-CHMI activities as only 10/17 were greater than −1.5.