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. Author manuscript; available in PMC: 2015 Dec 21.
Published in final edited form as: Compr Physiol. 2011 Apr;1(2):971–993. doi: 10.1002/cphy.c100053

Figure 9.

Figure 9

Two-dimensional M-mode echocardiographs of B2−/− mice and B2+/+ mice with sham coronary ligation (sham) or heart failure induced by coronary artery ligation. ACE inhibitor ramipril (2.5 mg/kg/day) reduced LV chamber size and thickeness in B2+/+, but only marginally in B2−/−, indicating an important role of kinin in the cardoprotective effects of ACE inibition in heart failure model. IS indicates interventricular septum; DD, left ventricular (LV) diastolic dimension; and PW, LV posterior wall. (Reprinted from Yang et al. (311).]