IL-10 timeline for each of the 40 UPN (y axes). Times of IL-10 measurements (months after prophylaxis discontinuation, x axes) are shown as vertical tick marks with the line to the right indicating the respective IL-10 measurement. The red lines indicate undetectable IL-10 levels (<2 pg/ml, below the assay sensitivity, see Materials and Methods). Black lines indicate detectable IL-10, with width proportional to the logarithm of IL-10 value. Black diamonds indicate the time of CMV-dz onset, in the 13 patients who developed CMV-dz. The top 13 lines show the 13 patients who developed CMV-dz. Vertical red tick marks indicate time points in which CMV DNA was detected. The first 3 lines show patients selected retrospectively after observing CMV-dz. (* symbol identifies patients from Ref. [12] study) All other patients were followed 12 months post-transplant without developing CMV-dz.