Figure 4.

Gravimetric moisture sorption/desorption isotherms of morphinanes and their hydrates at 25 °C: (a) M, (b) C, (c) D, (d) MCl, (e) CCl, and (f) DCl. The gray circles represent data points recorded at equilibrium conditions (see experimental section), and × indicates measurements where equilibrium conditions have not been reached within the set time limit (48 h). The order and direction of the sorption (increasing RH) and desorption (decreasing RH) cycles are indicated by the numbers and arrows, respectively.