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. 2015 Nov 2;4(2):137–146. doi: 10.1007/s40120-015-0037-x

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© The Author(s) 2015

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Slower dose titration as a management strategy. a DMF = delayed-release dimethyl fumarate (also known as gastro-resistant DMF). b One respondent had not used the recommended titration of 120 mg BID for 7 days. AE adverse event, BID twice daily, GI gastrointestinal