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. 2015 Dec 14;8:3721–3730. doi: 10.2147/OTT.S89779

Figure 4.

Figure 4

NRBP1 reduces downstream gene expression of Wnt/β-catenin signaling pathway in breast cancer.

Notes: mRNA (A) and protein (B) expression of Cyclin D1 or c-Myc in MCF-7 and MDA-MB-231 cells transfected with vector control or NRBP1 plasmid for 24 hours. mRNA (C) and protein (D) expression of Cyclin D1 or c-Myc in MCF-7 and MDA-MB-231 cells transfected with scramble siRNA or NRBP1 siRNA for 24 hours. β-actin was used as the loading control. *P<0.05 compared with control cells.

Abbreviation: NRBP1, nuclear receptor binding protein 1.