Table 1.
Correlation between NRBP1 and clinicopathological features
| Characteristics | Patient number (%) | NRBP1 low expression (%) | NRBP1 high expression (%) | P-value |
|---|---|---|---|---|
| Age (years) | 0.296 | |||
| <50 | 49 (53.3) | 27 (55.1) | 22 (44.9) | |
| ≥50 | 43 (46.7) | 19 (44.2) | 24 (55.8) | |
| Menopausal status | 0.053 | |||
| Pre-menopausal | 35 (38.0) | 13 (37.1) | 22 (62.9) | |
| Post-menopausal | 57 (62.0) | 33 (57.9) | 24 (42.1) | |
| Histological grade | <0.001 | |||
| G1 | 23 (25.0) | 4 (17.4) | 19 (82.6) | |
| G2 | 38 (41.3) | 20 (52.6) | 18 (47.4) | |
| G3 | 31 (33.7) | 22 (71.0) | 9 (29.0) | |
| Histological type | 0.216 | |||
| Ductal | 78 (84.8) | 42 (53.8) | 36 (46.2) | |
| Lobular | 11 (12.0) | 3 (27.3) | 8 (72.7) | |
| Others | 3 (3.2) | 1 (33.3) | 2 (66.7) | |
| TNM stage | 0.014 | |||
| I | 16 (17.4) | 3 (18.8) | 13 (81.2) | |
| II | 21 (22.8) | 10 (47.6) | 11 (52.4) | |
| III + IV | 55 (59.8) | 33 (60.0) | 22 (40.0) | |
| Tumor diameter (cm) | 0.007 | |||
| <2 | 49 (17.4) | 18 (36.7) | 31 (63.3) | |
| ≥2 | 43 (82.6) | 28 (65.1) | 15 (34.9) | |
| Nodal status | 0.029 | |||
| Negative | 32 (34.8) | 11 (34.4) | 21 (65.6) | |
| Positive | 60 (65.2) | 35 (58.3) | 25 (41.7) | |
| Recurrence | 0.004 | |||
| No | 68 (74.0) | 28 (41.2) | 40 (58.8) | |
| Yes | 24 (26.0) | 18 (75.0) | 6 (25.0) |
Abbreviations: G1, well differentiated; G2, moderately differentiated; G3, poorly differentiated; NRBP1, nuclear receptor binding protein 1; TNM, tumor, node, and metastasis system.