. Author manuscript; available in PMC: 2016 Jan 23.
Published in final edited form as: Nature. 2015 Jun 17;523(7561):486–490. doi: 10.1038/nature14590
Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms