Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Association of genes and susceptibility to autoantibodies against DNA*
| Gene | Chromosome (SNP) | Comment | OR* |
|---|---|---|---|
| HLA-DRB3 | 6 (rs2187668) | Confers autoantibodies even in asymptomatics | 2.23 |
| STAT4 | 2 (rs7574865) | Autoantibody propensity loci | 1.77 |
| IRF5 | 7 (rs10488631) | Only non-HLA conferring autoantibodies even in asymptomatics | 1.92 |
| ITGAM | 16 (rs9888739) | Autoantibody propensity loci | 1.80 |
Case versus control; from Chung et al, 2011 (58)
