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. Author manuscript; available in PMC: 2015 Dec 21.
Published in final edited form as: IEEE Trans Ultrason Ferroelectr Freq Control. 2015 Dec;62(12):2068–2078.

Fig. 1.

Fig. 1

Experimental setup used to study the effect of bubble removal pulses on histotripsy fractionation of soft tissue. Histotripsy treatment was delivered from a transducer composed of 112 individual 500 kHz modules arranged in a spherical cap pattern, while a separate 1 MHz transducer aligned confocally with the histotripsy array was used to generate bubble removal pulses. Treatments were performed on a tissue phantom constructed from 1% agarose hydrogel with a thin layer of red blood cells (RBCs) embedded within. This RBC layer was oriented parallel to the transducer axis such that the axial profile of histotripsy lesion development could be visualized.