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. 2015 Dec 16;10(12):e0145130. doi: 10.1371/journal.pone.0145130

Fig 7. Effects of Tongxinluo(TXL) on fibrotic mediators in spontaneously hypertensive rat(SHR) kidneys.

Fig 7

Representative images and quantitative analysis of(A) α-SMA,(B)collagen IV and (C) fibronectin immunostaining. PCR analysis of(D)TGFβ1 and (E) SMAD3.(F)Quantitative analysis of tubulointerstitial fibrosis. Scale bar, 20 μm. Data are mean±SEM; n = 10 rats per group, #P<0.05 and*P<0.05 vs. WKY and SHR groups, respectively. α-SMA, α-smooth muscle actin; PCR, polymerase chain reaction; TGFβ1,transforming growth factor β1;SMAD3, small mothers against decapentaplegic homolog 3;WKY, Wistar-Kyoto.