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. 2015 Dec 10;10(12):e0144774. doi: 10.1371/journal.pone.0144774

Table 2. Characteristics of the included articles.

Approach Ageyr Comorbid disease N (%) Follow-up duration, months Size of tumor cm Histologic type N (%) Depth of invasion N (%) Location of tumor N (%)
Reference median mean±SD, differentiated undifferentiated mucosa submucosa upper middle lower
Chiu et al [30] ESD 66.3±12.3 18(24.3) 27.0 1.9±0.5 66(89.2) 8(10.8)
gastrectomy 67.0±12.8 25(62.5) 77.6 2.5±0.8 19(47.5) 21(52.5)
Kim et al [31] ESD 62.0±10.3 76.7 127(89.4) 15(10.6) 135(95.1) 7(4.9) 9(6.3) 65(45.8) 68(47.9)
gastrectomy 56.7±12.0 65.5 54(76.1) 17(23.9) 62(87.3) 9(12.7) 8(11.3) 1(1.4) 62(87.3)
Etoh et al [32] EMR 84.2 34(69.4) 57 1.3±0.6 44(89.8) 5(10.2) 39(79.6) 10(20.4)
gastrectomy 82.2 25(56.8) 57 2.8±0.5 40(90.9) 4(9.1) 15(34.1) 29(65.9)
Choi et al [33] EMR 59.3±9.1 69(40.1) 81 1.6±1.0 156(90.7) 16(9.3) 172(100) 0(0) 11(6.4) 41(23.8) 120(69.8)
gastrectomy 58.4±10.3 126(33.3) 88 1.7±1.1 342(90.2) 37(9.8) 379(100) 0(0) 25(6.6) 93(24.5) 261(68.9)
Kim et al [34] ER 62.0±17.8 62(37.5) 49.2 2.5±0.9 156(94.5) 9(5.5) 130(78.8) 35(21.2) 10(6.1) 24(14.5) 131(79.4)
gastrectomy 60.0±11.9 135(46.1) 59.3 3.0±1.2 261(89.4) 31(10.6) 250(85.6) 42(14.4) 21(7.2) 42(14.4) 229(78.4)
Najmeh et al [35] ESD 68.3±11.3 2.0±0.7
gastrectomy 72.0±8.8 3.8±2.1

ER, endoscopic resection

ESD, endoscopic submucosal dissection

EMR, endoscopic mucosal resection

SD, standard deviation

Differentiated type denotes well-differentiated or moderately differentiated adenocarcinoma Undifferentiated type denotes poorly differentiated adenocarcinoma or signet ring-cell carcinoma.