Figure 6.
Effects of DOR gene silencing (siDOR) on the gene expression levels of MDR1 and the protein expression levels of P-gp. (A) Reverse transcription-quantitative polymerase chain reaction and western blot analyses. (B) Histograms presenting the relative expression levels of MDR1 and P-gp. Data are from three independent experiments and are presented as the means ± standard deviation. **P<0.05. DOR, δ opioid receptor; BEL/FU, BEL-7402/5-fluorouracil; MDR1, multidrug resistance 1; P-gp, P-glycoprotein.