Table I.
Spontaneous and radiation-induced chromosomal radiosensitivity values for controls (n=20) and cervical cancer patients (n=35) determined by micronucleus assay and evaluated using three scoring methods.
| Group | Automated
|
Semi-Automated A
|
Semi-Automated B
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| 0 Gy | 2 Gy | 4 Gy | 0 Gy | 2 Gy | 4 Gy | 0 Gy | 2 Gy | 4 Gy | |
| Controls | |||||||||
| Mean | 56 | 125 | 323 | 10 | 115 | 317 | 13 | 155 | 454 |
| SEM | 8 | 8 | 13 | 1 | 5 | 11 | 1 | 6 | 9 |
| Patients | |||||||||
| Mean | 66 | 144 | 320 | 12 | 124 | 327 | 14 | 179a | 506a,b |
| SEM | 7 | 9 | 14 | 1 | 4 | 10 | 1 | 5 | 12 |
a
P<0.05 vs. controls (Mann-Whitney test);
b
analysis performed on 33 instead of 35 patients due to insufficient binucleated cell number. SEM, standard error of the mean.