Table V.
Biochemical parameters of female rats in the 90 day repeated dose toxicity assessment.
| Group | ALB (g/dl) |
CHO (mg/dl) |
GLU (mg/dl) |
TG (mg/dl) |
GOT (U/I) |
GPT (U/I) |
PHOS (mM/l) |
BUN (mg/dl) |
CRE (mg/dl) |
ALP (U/I) |
T-BIL (mg/dl) |
Ca (mm/l) |
T.P (g/dl) |
Na+ (mEq/l) |
K+ (mEq/l) |
Cl− (mEq/l) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Control (0 mg/kg) |
4.36±0.59 | 66.91±3.60 | 94.54±3.43 | 64.94±2.80 | 122.58±5.11 | 47.99±2.69 | 5.11 0.57 |
15.82±2.25 | 0.36±0.04 | 100.60±4.77 | 0.18±0.01 | 8.59±0.33 | 7.24±0.12 | 133.20±1.48 | 4.92±0.41 | 95.75±3.72 |
| Low dose (100 mg/kg) |
4.54±0.22 | 61.28±3.45 | 95.61±2.11 | 62.90±4.06 | 123.31±4.25 | 40.37±6.88 | 4.90 0.43 |
15.98±1.89 | 0.43±0.08 | 102.53±3.45 | 0.15±0.02 | 8.24±0.53 | 7.26±0.34 | 131.97±0.64 | 4.63±0.25 | 97.32±2.42 |
| Intermediate dose (500 mg/kg) |
5.10±0.28 | 61.39±4.51 | 89.22±2.38 | 75.06±3.63 | 124.05±2.53 | 41.52±2.07 | 4.38 0.44 |
15.19±1.80 | 0.42±0.11 | 103.08±3.95 | 0.16±0.02 | 8.40±0.51 | 7.43±0.29 | 132.12±0.25 | 5.16±0.58 | 96.43±2.65 |
| High dose (1,000 mg/kg) |
4.13±0.27 | 60.65±2.46 | 99.19±3.65 | 70.10±3.23 | 140.03±5.66 | 63.07±2.97 | 5.16 0.26 |
16.96±1.51 | 0.39±0.03 | 151.46±7.79 | 0.20±0.02 | 8.69±0.40 | 7.31±0.29 | 132.18±0.72 | 5.40±0.36 | 95.33±1.97 |
| Satellite control (0 mg/kg) |
4.74±0.67 | 69.41±5.02 | 102.64±3.82 | 75.60±2.89 | 132.82±3.58 | 50.32±2.24 | 4.12 0.38 |
17.00±1.93 | 0.36±0.03 | 111.36±1.49 | 0.16±0.01 | 9.73±0.61 | 7.75±0.36 | 133.44±0.26 | 5.48±0.37 | 96.48±1.51 |
| High dose satellite (1,000 mg/kg) |
4.93±0.52 | 63.90±2.95 | 104.88±1.08 | 80.06±1.38 | 141.02±1.82 | 69.82±3.94 | 4.86 0.51 |
14.28±0.81 | 0.46±0.04 | 124.04±3.78 | 0.18±0.01 | 8.83±0.77 | 7.30±0.25 | 133.62±0.18 | 5.76±0.22 | 100.56±1.09 |
Analysis of variance was used for statistical analysis. Data are presented as the mean ± standard deviation. P>0.05, compared with the respective control. ALB, albumin; CHO, cholesterol; GLU, glucose; TG, triglyceride; GOT, glutamate oxaloacetate transferase; GPT, glutamate pyruvate transferase; PHOS, phosphorus; BUN, blood urea nitrogen; CRE, creatinine; ALP, alkaline phosphatase; T-BIL, total bilirubin; Ca, calcium; TP, total protein; Na+, sodium; K+, potassium, Cl−, chloride.