Table VIII.

Bone marrow values determined using a mammalian erythrocyte micronucleus test in mice.

Parameter	24 h following treatment						48 h following treatment
	Negative control (corn oil)		CEC (20,00 mg/kg)		Positive control (cyclophosphamide) 40 mg/kg		Negative control (corn oil)		CEC (20,00 mg/kg)		Positive control (cyclophosphamide) 40 mg/kg
	M	F	M	F	M	F	M	F	M	F	M	F
Total erythrocytes counted (n)	200.00±0.00	200.00±0.00	200.00±0.00	200.00±0.00	200.00±0.00	200.00±0.00	200.00±0.00	200.00±0.00	200.00±0.00	200.00±0.00	200.00±0.00	200.00±0.00
Immature erythrocytes obtained (n)	106.00±6.56	104.00±7.58	106.40±6.23	106.40±4.51	98.80±2.59	97.20±2.59	107.20±5.59	100.40±2.88	104.40±5.77	104.40±4.28	99.20±4.09	99.60±3.91
Mature erythrocytes obtained (n)	94.00±0.56	96.00±7.58	93.60±6.23	93.60±4.51	101.20±2.59	104.80±2.77	92.80±5.59	99.60±2.88	95.60±5.97	95.60±4.28	100.80±4.09	100.40±3.91
Immature erythrocytes in total erythrocytes (%)	53.00±3.28	52.00±3.79	53.20±3.11	53.20±2.25	49.40±1.29	48.60±1.29	53.60±2.79	50.20±1.44	52.20±2.89	52.20±2.14	49.60±2.04	49.10±1.24
Total immature erythrocytes counted (n)	2,000.00±0.00	2,000.00±0.00	2,000.00±0.00	2,000.00±0.00	2,000.00±0.00	2,000.00±0.00	2,000.00±0.00	2,000.00±0.00	2,000.00±0.00	2,000.00±0.00	2,000.00±0.00	2,000.00±0.00
Total micronuclei present in immature erythrocytes (n)	1.00 0.00	1.20±0.45	1.00±0.71b	1.00±0.71b	56.20±2.95a	56.20±2.95a	0.60±0.54	1.33±0.58	0.80±0.49b	1.33±0.5b	45.80±4.44a	45.40±8.29a

Analysis of variance was used for statistical analysis. Data are presented as the mean ± standard deviation.

^aP<0.01, compared with the respective control;

^bP>0.05, compared with the respective negative control. CEC, curcuminoid-essential oil complex; M, male; F, female.