Table VIII.
Parameter | 24 h following treatment
|
48 h following treatment
|
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Negative control (corn oil)
|
CEC (20,00 mg/kg)
|
Positive control (cyclophosphamide) 40 mg/kg
|
Negative control (corn oil)
|
CEC (20,00 mg/kg)
|
Positive control (cyclophosphamide) 40 mg/kg
|
|||||||
M | F | M | F | M | F | M | F | M | F | M | F | |
Total erythrocytes counted (n) | 200.00±0.00 | 200.00±0.00 | 200.00±0.00 | 200.00±0.00 | 200.00±0.00 | 200.00±0.00 | 200.00±0.00 | 200.00±0.00 | 200.00±0.00 | 200.00±0.00 | 200.00±0.00 | 200.00±0.00 |
Immature erythrocytes obtained (n) | 106.00±6.56 | 104.00±7.58 | 106.40±6.23 | 106.40±4.51 | 98.80±2.59 | 97.20±2.59 | 107.20±5.59 | 100.40±2.88 | 104.40±5.77 | 104.40±4.28 | 99.20±4.09 | 99.60±3.91 |
Mature erythrocytes obtained (n) | 94.00±0.56 | 96.00±7.58 | 93.60±6.23 | 93.60±4.51 | 101.20±2.59 | 104.80±2.77 | 92.80±5.59 | 99.60±2.88 | 95.60±5.97 | 95.60±4.28 | 100.80±4.09 | 100.40±3.91 |
Immature erythrocytes in total erythrocytes (%) | 53.00±3.28 | 52.00±3.79 | 53.20±3.11 | 53.20±2.25 | 49.40±1.29 | 48.60±1.29 | 53.60±2.79 | 50.20±1.44 | 52.20±2.89 | 52.20±2.14 | 49.60±2.04 | 49.10±1.24 |
Total immature erythrocytes counted (n) | 2,000.00±0.00 | 2,000.00±0.00 | 2,000.00±0.00 | 2,000.00±0.00 | 2,000.00±0.00 | 2,000.00±0.00 | 2,000.00±0.00 | 2,000.00±0.00 | 2,000.00±0.00 | 2,000.00±0.00 | 2,000.00±0.00 | 2,000.00±0.00 |
Total micronuclei present in immature erythrocytes (n) | 1.00 0.00 | 1.20±0.45 | 1.00±0.71b | 1.00±0.71b | 56.20±2.95a | 56.20±2.95a | 0.60±0.54 | 1.33±0.58 | 0.80±0.49b | 1.33±0.5b | 45.80±4.44a | 45.40±8.29a |
Analysis of variance was used for statistical analysis. Data are presented as the mean ± standard deviation.
P<0.01, compared with the respective control;
P>0.05, compared with the respective negative control. CEC, curcuminoid-essential oil complex; M, male; F, female.