Table 1.
Parameter | Sham + IgG (n = 8) | Sham + anti-FKN (n = 6) | MI + IgG (n = 7) | MI + anti-FKN (n = 7) |
---|---|---|---|---|
HR (beats min−1) | 691 ± 21 | 712 ± 14 | 708 ± 8 | 675 ± 29 |
BW (g) | 30.9 ± 1.7 | 27.8 ± 0.8 | 29.7 ± 0.7 | 31.3 ± 0.8 |
LVEF (%) | 80.40 ± 2.8 | 79.40 ± 3.9 | 37.44 ± 4.3** | 57.23 ± 6.9†† |
LVDd (mm) | 2.75 ± 0.09 | 2.80 ± 0.12 | 5.03 ± 0.31** | 3.74 ± 0.35†† |
LVDs (mm) | 1.26 ± 0.09 | 1.10 ± 0.11 | 4.30 ± 0.44*** | 2.48 ± 0.44† |
PWTd (mm) | 0.99 ± 0.08 | 0.90 ± 0.04 | 0.76 ± 0.04* | 0.95 ± 0.07 |
LVAs (mm2) | 0.90 ± 0.16 | 0.90 ± 0.22 | 9.68 ± 1.97** | 4.27 ± 1.18† |
LVAd (mm2) | 4.64 ± 0.59 | 4.1 ± 0.25 | 14.66 ± 2.44** | 8.75 ± 1.51 |
SF (%) | 54.17 ± 2.70 | 59.1 ± 4.18 | 19.04 ± 4.74*** | 33.66 ± 6.29 |
Abbreviations: BW, body weight; FKN, fractalkine; HR, heart rate; LVAd, left ventricular area at diastole; LVAs, left ventricular area at systole; LVDd, left ventricular dimension at diastole; LVDs, left ventricular dimension at systole; LVEF, left ventricular ejection fraction; MI, myocardial infarction; PWTd, posterior wall thickness at diastole; and SF, shortening fraction.
P < 0.05,
P < 0.01 and
P < 0.005 versus sham MI;
P < 0.05 and
P < 0.01 versus MI + IgG.