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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: J Trauma Acute Care Surg. 2015 Dec;79(6):897–904. doi: 10.1097/TA.0000000000000792

Figure 1. Schematic of profound shock model.

Figure 1

Animals after cannulation underwent hemorrhage form 5 minutes reduce blood pressure to a mean arterial pressure of less than 35 mmHg, 30 minutes of shock, 5 minutes of resuscitation, and 15 minutes of observation. During resuscitation animals were randomized to either plasma or saline with an initial 10% estimated blood volume bolus followed by an addition as needed saline resuscitation to obtain a mean arterial pressure greater than 30.

MAP= mean arterial pressure in mmHG

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