Fig 6. Egfr silencing reversed the promoting effect of miR-sc8 inhibitor on SC proliferation and migration.
(A) Representative Western blot images showing the protein expression of Egfr in primary SCs that had been transfected with anti-control plus siRNA control, anti-miR-sc8 plus siRNA control, or anti-miR-sc8 plus Egfr siRNA. GAPDH served as a loading control. (B) Histogram compared cell proliferation of primary SCs after transfection with miR-sc8 inhibitors (Anti-miR-sc8) and with inhibitor control in the presence or absence of Egfr siRNA (si Egfr), respectively. (C) Histogram compared cell migration of primary SCs after transfection with miR-sc8 inhibitor (Anti-miR-sc8) and with inhibitor control in the presence or absence of Egfr siRNA (si Egfr), respectively. *P<0.05 versus inhibitor control (Anti-Con) and siRNA control (si Con).