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. 2015 Dec 21;10(12):e0145306. doi: 10.1371/journal.pone.0145306

Fig 4. CORMs decrease HLA class I Ab-induced VCAM-1 expression in HUVECs.

Fig 4

Confluent HUVECs were incubated with W6/32 or isotype control (10 μg/ml) for 18 h in the presence or absence of CORM-2 (25 μM), iCORM-2 (25 μM), CORM-3 (75 μM) or iCORM-3 (75 μM), as indicated. Cells were lysed and subjected to RT-PCR analysis. The fold induction of mRNA levels is indicated. Data are represented as mean ± SEM from three independent experiments. * p≤ 0.05, significant differences CORM-2/3 versus W6/32; ** p≤ 0.05, iCORM-2/3 versus CORM2/3.