. 2015 Dec 21;10(12):e0144990. doi: 10.1371/journal.pone.0144990

Table 1. Values, descriptions and sources of the parameters driving the base metapopulation model of transmission.

(i = {TC; MB; UJ; NK; BB; MP}) Values in parentheses are the assumed ranges for the parameter sensitivity analysis.

Parameter	Description	Value	Source
N	Population size for the six patches	2.5 × 10⁶	[52, 53]
μ	Mortality/birth Rate	$\frac{105}{10000}$	[43]
δ	Natural recovery period	26 weeks (24, 28)	[44–46]
σ ₁	Period between liver stage and blood-stage	7 days (5–10)	[47–49]
σ ₂	Period between blood-stage and onset of gametocytemia	2 weeks (1.8, 2.2)	[44, 50]
r	AL elimination half-life	6 days (4, 8)	[51]
τ	Time to seek treatment	1/2 week	Expert opinion
p	Proportion of local infected population receiving treatment	0.95	[35, 36]
pf _yr	Proportion of foreign infected population that receive treatment in a local patch	pf ₁ = 0.5655(0.5652, 0.5658) (pre April 2005)pf ₂ = 0.5500 (0.5494, 0.5506) (post April 2005)	Estimated from model fitting process
seas _i	Seasonal forcing function	Derived from data	[38]
β _i	Annual number of mosquito bites per person x proportion of bites testing positive for sporozoites for patch i	β _TC = 0.334 (0.244, 0.425) β _MB = 2.178 (2.056, 2.300) β _UJ = 0.805 (0.700, 0.910) β _NK = 1.330 (1.310, 1.350) β _BB = 8.304 (7.903, 8.705) β _MP = 94.999 (93.327, 96.671)	Estimated from model fitting process
$\frac{1}{α}$	Rate of movement between sub-patch 2 and sub-patch 1	2 weeks⁻¹(1.75, 2.25)	Expert opinion
$\frac{1}{k}$	Rate of movement between 5 Mpumalanga municipalities	1/48.603 (1/51.328, 1/45.787) weeks⁻¹	Estimated from model fitting process
$\frac{1}{v_{y}}$	Maputo residents: Rate of movement between Maputo and 5 Mpumalanga municipalities	$\frac{1}{v_{1}} = 1 / 1258.828 {weeks}^{- 1} (1 / 1261.249, 1 / 1256.407)$ (pre-April 2005) $\frac{1}{v_{2}} = 1 / 319.042 {weeks}^{- 1} (1 / 322.796, 1 / 315.333)$ (post April 2005)	Estimated from model fitting process
$\frac{1}{z}$	Mpumalanga residents: Rate of movement between 5 Mpumalanga municipalities and Maputo	$\frac{1}{z} = 1 / 765.19 {weeks}^{- 1}$	Estimated from model fitting process
fwgt	Foreign movement weight intensity	8.385 (8.232, 8.537)	Estimated from model fitting process
lwgt	Local movement weight intensity	2.613 (2.607, 2.618)	Estimated from model fitting process
vc[i, t]	vccov[i, t] × vef
vccov[i, t]	Vector Control Coverage	0.22–0.90	Derived from data
vef	Effectiveness of vector control	0.900 (0.897, 0.903)	Estimated from model fitting process