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. 2016 Feb 6;6(1):20150070. doi: 10.1098/rsfs.2015.0070

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© 2015 The Author(s)

Published by the Royal Society. All rights reserved.

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Figure 5. — TEM micrographs of collagen matrices. In SBF + Fet-mineralized collagen matrices, mineral was deposited as small clusters within the collagen matrix (middle column). High magnification shows each mineral inclusion to be composed of many randomly aligned nanocrystals. In SBF-mineralized collagen matrices, mineral deposits were found only on the collagen surface, in some cases penetrating up to 1 µm into the matrix. High magnification showed the formation of clusters of crystals near the matrix surface. Mineral crystals were not observed in Unmin collagen matrices. Scale bars for top row are 1 µm, and scale bars for bottom row are 500 nm.