Table 1.
Characteristics of Subset of HANDLS Participants Overall and by Race.
| Characteristic | Overall (N=376) | Whites1 (N=164) | Blacks1 (N=212) | P-value |
|---|---|---|---|---|
| Age (y) | 48.6 ± 9.2 | 49.3 ± 9.3 | 48.1 ± 9.1 | 0.18 |
| Male sex (%) | 166 (44.2) | 72 (43.9) | 94 (44.3) | 0.93 |
| Body Mass Index (kg/m2) | 29.6 ± 7.6 | 30.1 ± 7.4 | 29.3 ± 7.8 | 0.31 |
| Household income < 25% poverty line (%) | 159 (42.3) | 54 (32.9) | 105 (49.5) | 0.001 |
| Current smoker (%) | 176 (46.8) | 74 (45.1) | 102 (48.1) | 0.45 |
| Osteoporosis diagnosis (%) | 12 (3.2) | 9 (5.5) | 3 (1.4) | 0.04 |
| Prescribed osteoporosis therapy (%) | 10 (2.7) | 6 (3.7) | 4 (1.9) | 0.29 |
| Postmenopausal (% of women) | 108 (51.4) | 52 (56.5) | 56 (47.5) | 0.21 |
| Prescribed HRT (% of women) | 5 (2.4) | 2 (2.2) | 3 (2.5) | 0.81 |
| Microalbuminuria (%) | 4 (1.1) | 2 (1.2) | 2 (0.9) | 0.99 |
| eGFR <60 ml/min/m2 (%) | 26 (6.9) | 9 (5.5) | 17 (8.0) | 0.35 |
| Prescribed antiepileptic agents (%) | 3 (0.8) | 2 (1.2) | 1 (0.5) | 0.42 |
| Prescribed glucocorticoids (%) | 5 (1.3) | 1 (0.6) | 4 (1.9) | 0.28 |
| Dietary vitamin D intake (IU/day) | 154 ± 181 | 164 ± 223 | 146 ± 141 | 0.37 |
| Dietary calcium intake (mg/day) | 745 ± 568 | 761 ± 601 | 732 ± 542 | 0.62 |
| Femoral neck bone mineral density (g/cm2) | 1.00 ± 0.19 | 0.95 ± 0.16 | 1.04 ± 0.19 | <0.001 |
| Serum calcium (mg/dL) | 9.3 ± 0.4 | 9.3 ± 0.4 | 9.3 ± 0.4 | 0.63 |
| Parathyroid hormone (pg/mL)† | 36 (29, 47) | 34 (27, 45) | 38 (30, 48) | 0.01 |
| 25D3 (ng/mL) | 21.6 ± 10.8 | 27.5 ± 11.3 | 17.0 ± 7.8 | <0.001 |
| 24,25D3 (ng/mL) | 2.7 ± 1.8 | 3.6 ± 2.0 | 2.1 ± 1.3 | <0.001 |
| VMR (24,25(OH)2D3/25D3 ratio) × 100 | 12.1 ± 3.7 | 12.5 ± 3.4 | 11.9 ± 4.0 | 0.16 |
1
There were no statistically significant differences between any of the characteristics of white HANDLS subjects included in this study compared to non-included whites, and no differences between included and non-included black HANDLS subjects.
HRT = hormone replacement therapy
Table shows means ± standard deviations,
†
median (quartile 1, quartile 3), or number (percentage).