Table 4.

Gene alterations.

	AKT1	APC	ATM	BRCA2	cKIT	cMET	CTNNB1	EGFR	ERBB4	JAK3	KDR	TP53
# positive	1	1	1	1	1	1	9	1	1	1	1	13
Total tested	28	29	28	6	34	29	28	31	29	28	28	28
% total	3.6	3.4	3.6	16.7	2.9	3.4	32.1	3.2	3.4	3.6	3.6	46.4

Notes: Gene alterations were considered to be pathogenic or presumed pathogenic. Mutations of unknown significance, or believed to be benign (synonymous or missense), based on the ACCMG descriptions, were not reported. The test is not designed to distinguish somatic versus germline origin of the alteration. Genes tested for which no alterations were identified included ABL1, ALK, BRAF, BRCA1, CDH1, CSF1R, ERBB2, FBXW7, FGFR1, FGFR2, FLT3, GNA11, GNAQ, GNAS, HNF1A, HRAS, IDH1, JAK2, KRAS, MLH1, MPL, NOTCH1, NPM1, NRAS, PDGFRA, PIK3CA, PTEN, PTPN11, RB1, RET, SMAD4, SMARCB1, SMO, STK11, and VHL.