Figure 4.

Effect of unflavored waterpipe exposed rat on heart ventricular tissue. A: ultrathin section of ventricular cardiomyocytes of air-exposed rat. M: mitochondrion with normal cristae, S: sarcomeres, Z: Z-line. Magnification:62500x. B: ultrathin section of ventricular cells of unflavored waterpipe exposed rat, showing pleomorphic mitochondria. Arrows indicate deposited material. Magnification 5000x. C: ultrathin section of ventricular cells of flavored waterpipe exposed rat. The two areas enclosed by trapezoidal shapes denote partial disruption of the Z-disc. Arrows indicate partially disrupted mitochondria. C: capillary. Magnification: 5000x. D: ultrathin section of ventricular cells of unflavored waterpipe exposed rat after the recovery period, showing partial recovery of cardiac muscle fiber. Arrows indicate deposited material. The triangle indicates enlarged and pleomorphic mitochondria with partially disrupted cristae. M: mitochondrion, S: sarcomere Magnification: 25000x