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. 2015 Dec 22;6:387. doi: 10.3389/fphys.2015.00387

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Copyright © 2015 Harrell, Johansson, Evans, Sebranek, Walker, Eldridge, Serlin and Schrage.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ACh responses with combined inhibition. Change in forearm vascular conductance (ΔFVC) with intra-arterial ACh infusion and combined NOS-COX inhibition (l-NMMA and Keto). (A) ΔFVC was not different between lean (n = 46) and obese (n = 29) adults (same as Figure 1). (B) ΔFVC with combined NOS-COX inhibition was greater in obese adults (n = 29) than lean adults (n = 46) at 4 μg100⁻¹ g min⁻¹. ^*Significant group difference, p < 0.05.