Table 1.
Pairwise hypergeometric probability test shows a statistically significant overlap in differentially expressed genes between msl2msl3 and crl and between crl and ggps1.
| Change compared to the wild type | Mutant 1 (Number of genes) | Mutant 2 (Number of genes) | Number of genes altered in both Mutant 1 and Mutant 2 | Hypergeometric probability |
|---|---|---|---|---|
| Up-regulated | msl2msl3 (931) | crl (670) | 243 | 4.48 e−55 |
| Up-regulated | msl2msl3 (931) | ggps1 (1117) | 57 | 0.95 |
| Up-regulated | crl (670) | ggps1 (1117) | 124 | 6.88 e−44 |
| Down-regulated | msl2msl3 (520) | crl (211) | 34 | 1.27 e−20 |
| Down-regulated | msl2msl3 (520) | ggps1(1266) | 37 | 0.021 |
| Down-regulated | crl (211) | ggps1 (1266) | 44 | 2.99 e−16 |
Probability of the observed overlap based on size of the differentially expressed gene list for each (in parentheses) was calculated. Gray shading indicates significance with a cutoff of 0.01.