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Mammary carcinogenesis in N-methyl-N-nitrosourea injected rats
| Groups | Cancer incidence (%) | Cancer load number/rat (mean ± SEM) | Latency range (days) |
| P-UN (n = 6) | 16* | 0.167 | 121 |
| P-IGF-I (n = 6) | 83 | 2.17 ± 0.75 | 57–176 |
| AMV (n = 6) | 100 | 2.20 ± 0.45 | 92–217 |
Mammary tumor incidence, latency, and load in untreated parous rats (P-Un), parous rats treated with insulin-like growth factor -I, and in virgin rats that were age matched with the parous animals (AMV). *P < 0.05 versus P-IGF-I and AMV.
