Table 1.

Genotype frequencies for CYP1A1 among African-American and white participants in the Carolina Breast Cancer Study (1993–1996)

	African-Americans		Whites
	Cases (n = 271)	Controls (n = 285)	Cases (n = 417)	Controls (n = 417)
M1 locus
wt/wt	155 (59%)	165 (59%)	327 (79%)	325 (78%)
wt/M1	93 (35%)	102 (36%)	78 (19%)	83 (20%)
M1/M1	17 (6%)	13 (5%)	8 (2%)	7 (2%)
Missing	6	5	4	2
Chi-square test, P*		0.65		0.89
M2 locus
wt/wt	259 (96%)	274 (96%)	385 (92%)	378 (90%)
wt/M2	12 (4%)	11 (4%)	29 (7%)	37 (9%)
M2/M2	0	0	3 (1%)	2 (1%)
Missing	0	0	0	0
Fisher's exact test, P*		0.83		0.61
M3 locus
wt/wt	218 (82%)	227 (81%)	412 (99.8%)	413 (99.6%)
wt/M3	47 (18%)	47 (17%)	1 (0.2%)	1 (0.2%)
M3/M3	0	6 (2%)	0	1 (0.2%)
Missing	6	5	4	2
Fisher's exact test, P*		0.06		0.99
M4 locus
wt/wt	267 (98.5%)	278 (97.5%)	378 (90.7%)	377 (90%)
wt/M4	3 (1.1%)	7 (2.5%)	38 (9.1%)	40 (10%)
M4/M4	1 (0.4%)	0	1 (0.2%)	0
Missing	0	0	0	0
Fisher's exact test, P*		0.28		0.91

Data presented as n (%). wt, wild type. * Comparing cases and controls.