FIGURE 1.

Cumulative survival of mice infected with Candida albicans and treated with atorvastatin. BALB/c mice received an injection of C. albicans and were treated either with a single co-injection of atorvastatin, 5 days pre-infection or a 5 days post-infection atorvastatin regimen. A group infected with C. albicans but not treated with atorvastatin was also included. A mouse group injected solely with PBS, as a negative control, showed a 100% survival rate (not shown). Day 0 indicates the day of infection. Mice were monitored for 18 days after infection.