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. 2015 Dec 4;47(12):e197. doi: 10.1038/emm.2015.88

Figure 6.

Figure 6

Blockade of TNF-α secretion in co-cultured FLS or chondrocytes. Mouse chondrocytes or FLS were infected with or without 800 MOI of Ad-C or Ad-Epas1 and incubated with FLS (a) or chondrocytes (b), respectively. After 12 h, the indicated amounts (μg) of TNF-α-neutralizing antibody were added. After an additional 12 h, the transcripts of the indicated catabolic factors were detected by RT-PCR and qRT-PCR. Values are presented as means±s.e.m. (*P<0.05, **P<0.005).