Table 1.
Minimum inhibitory concentrations (MICs) of five candidate compounds against planktonic mode of Candida strains.
| C. albicans | C. glabrata | C. dubliniensis | C. tropicalis | C. kusei | C. palapsilosis | |
|---|---|---|---|---|---|---|
| Bay11-7082 | 7.8 | 7.8 | 3.9 | 7.8 | 3.9 | 3.9 |
| Bay11-7085 | 3.9 | 3.9 | 3.9 | 3.9 | 3.9 | 3.9 |
| Sanguinarine | <1 | <1 | <1 | <1 | <1 | <1 |
| Ellipticine | 7.8 | 7.8 | 3.9 | 15.6 | 7.8 | 7.8 |
| CV-3988 | 7.8 | 7.8 | 31.3 | 31.3 | 15.6 | 15.6 |
| AMB | 3.9 | |||||
| (μM) | ||||||
Sanguinarine, sanguinarine chloride hydrate; AMB, amphotericin B; MICs, minimal concentration of compound resulting in >50% growth inhibition. MICs were determined by ATP measurement after 24 h of incubation. The data were analyzed and evaluated from 3 biological replicate in triplicate (n = 3).