Table 2.

Analysis of means for all datasets with Welch two sample T-test

Parameter	p - values for a confidence interval of 95%
	(1)ME vs NE	(2)Random vs ME	(3)Random vs NE	(4) MP vs ME	(5) NP vs NE
R (Arg)	0.0029	0.0762	0.0001	0.0241	0.4226
H (His)	0.0362	0.1046	0.1074	0.5636	0.7906
K (Lys)	0.0000	0.0113	0.0000	0.4098	0.4818
D (Asp)	0.0890	0.6994	0.0079	0.7091	0.0030
E (Glu)	0.9289	0.2681	0.0838	0.6696	0.4072
S (Ser)	0.2953	0.5024	0.3546	0.9630	0.8954
T (Thr)	0.4077	0.1867	0.3509	0.2199	0.4523
N (Ans)	0.1878	0.7647	0.0101	0.5880	0.4944
Q (Gln)	0.1509	0.9483	0.0039	0.8471	0.8185
C (Cys)	0.1821	0.0003	0.0000	0.0316	0.0075
G (Gly)	0.6979	0.2576	0.4620	0.3509	0.8450
P (Pro)	0.3156	0.5165	0.3781	0.2103	0.4271
A (Ala)	0.2121	0.0066	0.0000	0.1092	0.0756
V (Val)	0.0993	0.0019	0.2903	0.0550	0.1854
I (Ile)	0.2657	0.0068	0.0352	0.1286	0.3275
L (Leu)	0.1374	0.1182	0.0000	0.5549	0.2322
M (Met)	0.0017	0.0725	0.0000	0.0282	0.2477
F (Phe)	0.6997	0.4713	0.0765	0.7890	0.5818
Y (Tyr)	0.0023	0.5245	0.0000	0.8318	0.0938
W (Trp)	0.0889	0.9443	0.0244	0.5782	0.1221
Isoe.Point	0.0425	0.5190	0.5190	0.0425	0.3221
gravy	0.0672	0.0010	0.0000	0.0672	0.0514
Aliph. Index	0.0086	0.0000	0.0000	0.0086	0.8550

Values under p-value under 0.05 are writen in bold. IC = 95%, H0 = Difference in means is cero. Hi = Difference in means is not equal to zero. Metalloproteinases epitopes = ME, Neurotoxin epitopes = NE, Metalloproteinase proteins = MP, Neurotoxin proteins = NP, Random = Random sequences.