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. 2015 Dec 22;9:485. doi: 10.3389/fncel.2015.00485

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Copyright © 2015 Juranek, Daffu, Wojtkiewicz, Lacomis, Kofler and Schmidt.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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High magnification images of white/gray matter showing triple staining for RAGE and its ligands S100B, CML, and HMGB1. Immunostaining for RAGE (red) and its ligands S100B (green) and CML or HMGB1 (blue) revealed low immunoexpression in control tissue (A and C) and high immunoexpression in ALS tissue (B and D). Sections are representative of n = 6 control and n = 5 ALS tissue samples per condition. Scale bar: 100 μm.