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. 2015 Dec 22;9:483. doi: 10.3389/fncel.2015.00483

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Copyright © 2015 González-Garrido, Vega, Mercado, López and Soto.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effect of aminoglycosides on the ASIC current in SGNs. (A) Sustained application of 100 μM St produced a reversible reduction in the I_peak and the τ_des. (B) Sustained application of 100 μM Neo produced similar effects but at a reduced potency. (C) Bar graph summarizing the actions of the aminoglycosides. The bars represent the means ± SE of the I_peak, the I_sus, the I_int, or the τ_des. The data are expressed as the percent-change relative to the control value (^∗P < 0.05, paired Student’s t-test). Differences between concentrations were evaluated via one-way ANOVA (^∗P < 0.05)