Fig 1. Neighbor-joining phylogenetic reconstruction of the HBV pre-S/S (A, N = 20), Pre-C/C (B, N = 11) and full genome (C, N = 3) using the bootstrap method.

Clustering is prominent between individual cases, indicating a greater degree of variation between individuals, than amongst each of their viral quasispecies. Bootstrap values greater than 70 were considered significant. Case #146 was excluded from analysis as only the pre-S1 region was sequenced.