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. Author manuscript; available in PMC: 2016 Aug 28.
Published in final edited form as: Eur J Med Chem. 2015 Jun 16;101:384–390. doi: 10.1016/j.ejmech.2015.06.031

Table 3.

Kinetic solubility assessment of compound 13, reserpine, tamoxifen, and verapamil in phosphate-buffered saline (PBS).

Compound Tested Solubility Limit (µM)1 Solubility Analysis
13 15.6 Low solubility
Reserpine 15.6 Low solubility
Tamoxifen 15.6 Low solubility
Verapamil >500 High solubility
1

Solubility limit corresponds to the highest concentration of test compound where no precipitate was detected.